An investigation into the binding and signalling properties of group I metabotropic glutamate receptors expressed recombinantly in mammalian cell lines
This Thesis investigates the G protein coupling profile of group I mGluRs using a novel 35S -GTPyS binding with subsequent Gcc subunit-specific immunoprecipitation protocol. This approach allows the quantitation of activation of individual G proteins or groups of G proteins to be assessed. Using thi...
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University of Leicester
2001
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696954 |