Synthesis of aminosterols structurally related to squalamine
Squalamine is a naturally occurring broad-spectrum antimicrobial agent isolated from the dogfish shark Squalus acanthias. It has been shown to have biological activity against both Gram-negative and Gram-positive bacteria, fungi, sexually transmitted diseases (STDs) and cancer. A flexible synthetic...
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University of Leicester
2001
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.696963 |