A study of the receptor tyrosine kinase Tie2 and its interaction with novel signalling intermediates

The receptor tyrosine kinase Tie2 is expressed predominantly in endothelial cells and has a role in blood vessel formation, remodelling and maturation. This receptor also has anti-apoptotic and anti-inflammatory effects on endothelial cells. To delineate the signalling pathways utilised by Tie2 two...

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Bibliographic Details
Main Author: Hughes, David Paul
Published: University of Leicester 2003
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697234