Mechanisms of action of the chemopreventive agent indole-3-carbinol in breast cell lines

The chemopreventive agent indole-3-carbinol (I3C) is found in cruciferous vegetables such as broccoli, cabbage and Brussels sprouts. Clinical trials have shown I3C to favourably alter urinary 2-OH:16a estrone ratios, which may prove beneficial for decreased risk of ER+ve breast cancer. However, mole...

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Bibliographic Details
Main Author: Howells, Lynne M.
Published: University of Leicester 2003
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697239