Concise syntheses of diflouroanalogues of cyclitols and sugars
The synthesis of (1 fl*,2f*,3S*,4S',)-5,5-dif luorocyclohexane-1,2,3,4-tetrol was accomplished with an overall yield of 20 % from trifluoroethanol over 8 steps featuring a key dehydrofluorination/metallation followed by trapping of aldehyde (scheme). The route based on a fluorinated building bl...
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University of Leicester
2006
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697334 |