The expression and function of RAGE and HMGB1 in airway structural cells in asthma
Asthma is characterised by airway hyperresponsiveness, airflow obstruction, chronic inflammation and airway remodelling, with an increase in airway smooth muscle (ASM) mass and contractility. ASM also releases mediators that support inflammation and remodelling. High-mobility group box 1 (HMGB1) is...
Main Author: | |
---|---|
Other Authors: | |
Published: |
University of Leicester
2015
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697418 |