The expression and function of RAGE and HMGB1 in airway structural cells in asthma

Asthma is characterised by airway hyperresponsiveness, airflow obstruction, chronic inflammation and airway remodelling, with an increase in airway smooth muscle (ASM) mass and contractility. ASM also releases mediators that support inflammation and remodelling. High-mobility group box 1 (HMGB1) is...

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Bibliographic Details
Main Author: Di Candia, Leonarda
Other Authors: Brightling, Christopher ; Challiss, John
Published: University of Leicester 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697418