Modulation of the mitogen activated protein kinase pathway spatiotemporal signalling components : influence on pathway activation behaviour using an agent based model

The subtleties of how the Mitogen Activated Protein Kinase works (MAPK) biochemical signalling pathway works, its emergent oscillatory behaviour and sensitivity is explained though an analysis of a computational agent based model that takes into account the distribution of the MAPK cascade component...

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Bibliographic Details
Main Author: Shuaib, Aban
Other Authors: Kiss-Toth, E. ; Holcombe, M.
Published: University of Sheffield 2016
Subjects:
572
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.698288