Modulation of the mitogen activated protein kinase pathway spatiotemporal signalling components : influence on pathway activation behaviour using an agent based model
The subtleties of how the Mitogen Activated Protein Kinase works (MAPK) biochemical signalling pathway works, its emergent oscillatory behaviour and sensitivity is explained though an analysis of a computational agent based model that takes into account the distribution of the MAPK cascade component...
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University of Sheffield
2016
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ndltd-bl.uk-oai-ethos.bl.uk-6982882018-11-08T03:19:51ZModulation of the mitogen activated protein kinase pathway spatiotemporal signalling components : influence on pathway activation behaviour using an agent based modelShuaib, AbanKiss-Toth, E. ; Holcombe, M.2016The subtleties of how the Mitogen Activated Protein Kinase works (MAPK) biochemical signalling pathway works, its emergent oscillatory behaviour and sensitivity is explained though an analysis of a computational agent based model that takes into account the distribution of the MAPK cascade components into multiple compartments.572University of Sheffieldhttps://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.698288http://etheses.whiterose.ac.uk/14404/Electronic Thesis or Dissertation |
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572 Shuaib, Aban Modulation of the mitogen activated protein kinase pathway spatiotemporal signalling components : influence on pathway activation behaviour using an agent based model |
description |
The subtleties of how the Mitogen Activated Protein Kinase works (MAPK) biochemical signalling pathway works, its emergent oscillatory behaviour and sensitivity is explained though an analysis of a computational agent based model that takes into account the distribution of the MAPK cascade components into multiple compartments. |
author2 |
Kiss-Toth, E. ; Holcombe, M. |
author_facet |
Kiss-Toth, E. ; Holcombe, M. Shuaib, Aban |
author |
Shuaib, Aban |
author_sort |
Shuaib, Aban |
title |
Modulation of the mitogen activated protein kinase pathway spatiotemporal signalling components : influence on pathway activation behaviour using an agent based model |
title_short |
Modulation of the mitogen activated protein kinase pathway spatiotemporal signalling components : influence on pathway activation behaviour using an agent based model |
title_full |
Modulation of the mitogen activated protein kinase pathway spatiotemporal signalling components : influence on pathway activation behaviour using an agent based model |
title_fullStr |
Modulation of the mitogen activated protein kinase pathway spatiotemporal signalling components : influence on pathway activation behaviour using an agent based model |
title_full_unstemmed |
Modulation of the mitogen activated protein kinase pathway spatiotemporal signalling components : influence on pathway activation behaviour using an agent based model |
title_sort |
modulation of the mitogen activated protein kinase pathway spatiotemporal signalling components : influence on pathway activation behaviour using an agent based model |
publisher |
University of Sheffield |
publishDate |
2016 |
url |
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.698288 |
work_keys_str_mv |
AT shuaibaban modulationofthemitogenactivatedproteinkinasepathwayspatiotemporalsignallingcomponentsinfluenceonpathwayactivationbehaviourusinganagentbasedmodel |
_version_ |
1718789783660003328 |