Assessing the physiological and pathological functions of tissue Transglutaminase using FRET analysis

Tissue Transglutaminase (TG2) is a cross-linking enzyme that links proteins by the formation of covalent bonds and confers resistance to proteolytic degradation. TG2 acts as a cell adhesion protein by binding to matrix fibronectin, cell surface heparan sulphates and integrins. TG2 has been implicate...

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Bibliographic Details
Main Author: Sharma, Shruti
Published: Aston University 2016
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.698907