Using machine learning and systems-biology approaches to analyse next-generation sequence data in cancers

The availability of exome sequence data for thousands of cancer samples has enabled the investigation of the sequence-level mutations that contribute to cancer. There is a need for strategies to analyse sequence data to gain new biological and clinical insights. This thesis investigates the use of m...

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Bibliographic Details
Main Author: Sutherland, Russel David
Other Authors: Lewis, Cathryn Mair ; Dobson, Richard James Butler
Published: King's College London (University of London) 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.700764