An investigation of the pharmacogenetic basis of toxicity to platinum chemotherapy agents

Background: Platinum-based chemotherapy is the main stay of first line treatment for a number of tumour types. However, toxicity is a significant issue, particularly haematological toxicity and sepsis leading to morbidity, hospital admissions and delay or loss in optimal chemotherapy regimens. Few s...

Full description

Bibliographic Details
Main Author: Corrigan, Adele
Other Authors: Sanderson, Jeremy ; Spicer, James Frederick
Published: King's College London (University of London) 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.700813