Regulation of CD38 by IRF4 in chronic lymphocytic leukemia

Genome‐wide association analysis identified rs872071, a common variant in the 3’UTR of IRF4, as tagging a risk allele for chronic lymphocytic leukaemia (CLL). The risk allele is significantly associated with expression of CD38, a poor prognostic marker in CLL. IRF4 is a transcription factor with ple...

Full description

Bibliographic Details
Main Author: Marr, Helen Judith
Published: University of Newcastle upon Tyne 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.701145