Building a rational model for the identification of allosteric sites

Allostery is the regulation of protein function, structure and/or flexibility that is induced by the binding of a ligand at a site distinct from the orthosteric site.1, 2 Interaction of a small molecule with these sites can bring greater selectivity as they are not conserved within a family and ther...

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Bibliographic Details
Main Author: Indey, Camille Roxanne Chevalier
Published: University of Strathclyde 2016
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.701546