A novel mechanism underlying prostate cancer progression : an investigation into the impact of insulin like growth factors (IGFs), PTEN and IGFBP2 on TMPRSS2:ERG fusion induction
Prostate cancer (PC) is the most commonly diagnosed male cancer in the UK. The transmembrane protease serine 2 (TMPRSS2) gene has been found fused to the ETS related gene (ERG), which codes for an oncogenic transcription factor in 50% of PC cases. Fusion puts the coding sequence of ERG under the con...
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University of Bristol
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.701807 |