Cardiolipin metabolism and mitochondrial structure and function in the pathogenesis of Barth syndrom
Tetralinoleoyl cardiolipin (Cl₄) is a mitochondrial membrane phospholipid associated with numerous mitochondrial structural and functional proteins. Synthesis involves remodelling by tafazzin, an acyltransferase encoded by the TAZ gene. TAZ mutations result in Barth syndrome (BTHS), a rare disorder...
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University of Bristol
2016
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.702121 |