The regulation of gene expression in response to ER stress

A disruption in endoplasmic reticulum (ER) homeostasis can lead to ER stress and the accumulation of misfolded proteins, which has been implicated with the development of diabetes and many other diseases. In reaction to this the cell mounts an adaptive response termed the unfolded protein response (...

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Bibliographic Details
Main Author: Elfowiris, Abdulsalam
Other Authors: Willars, Gary ; Herbert, Terence P.
Published: University of Leicester 2017
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.702706