A role for Cathepsin S in the pathogenesis of cystic fibrosis-like lung disease

Elevated levels of the cysteine protease cathepsin S (cat S) are found in Cystic fibrosis (CF) lung secretions, however, the role of cat S in CF lung disease is unclear. Cat S is capable of maintaining its activity at a neutral pH allowing it to remain active outside of the cell. Consequently, cat S...

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Bibliographic Details
Main Author: Brown, Ryan
Published: Queen's University Belfast 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.705650