Investigating the regulation of cohesin dynamics during meiotic prophase in C. elegans

The physical linking of sister chromatids after S-phase is known as sister chromatid cohesion (SCC) and is largely provided by the cohesin complex. The coordinated loss of SCC at anaphase onset is essential for correct chromosome segregation, a process mediated by proteolysis of the kleisin subunit...

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Bibliographic Details
Main Author: Crawley, Oliver
Other Authors: Martinez-Perez, Enrique
Published: Imperial College London 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.705759