Changes in the ATP-binding cassette efflux transporters of the blood-brain barrier in glioma challenge

The ATP-binding cassette (ABC) family of efflux transporters are expressed on the blood-facing (apical) surface of blood-brain barrier (BBB) endothelia and include P- glycoprotein (Pgp) and breast cancer resistance protein (BCRP). These neuro- protective transporters restrict the movement of compoun...

Full description

Bibliographic Details
Main Author: Georgian, Ana Ruxandra
Other Authors: Preston-Kennedy, Jane Elizabeth ; Abbott, Nancy Joan ; Begley, David John
Published: King's College London (University of London) 2014
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.705923