Changes in the ATP-binding cassette efflux transporters of the blood-brain barrier in glioma challenge
The ATP-binding cassette (ABC) family of efflux transporters are expressed on the blood-facing (apical) surface of blood-brain barrier (BBB) endothelia and include P- glycoprotein (Pgp) and breast cancer resistance protein (BCRP). These neuro- protective transporters restrict the movement of compoun...
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King's College London (University of London)
2014
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.705923 |