Structural and functional studies of human methionine adenosyltransferases

S-Adenosylmethionine (SAMe) is the principal methyl donor of the cell and is synthesized via an ATP-driven process by methionine adenosyltransferase (MAT) enzymes. It is tightly linked with cell proliferation in liver and colon cancer. In humans, there are three genes, MAT1A, MAT2A and MAT2B, which...

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Bibliographic Details
Main Author: Murray, Ben
Published: University of Liverpool 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.706623