Utilisation of an in vitro T-cell priming assay to characterise the effects of co-inhibitory signalling on the activation of antigen-specific T-cells
Hypersensitivity denotes a form of immune-mediated adverse reaction associated with a high degree of morbidity and mortality. Due to a lack of animal models, research has focussed on patient lymphocytes ex vivo. However, such studies bypass investigation of naïve T-cell activation. Subsequently, in...
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University of Liverpool
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.706696 |