Development of novel proximal tubule in vitro models to predict drug-induced nephrotoxicity
Drug-induced nephrotoxicity is a dose limiting factor and a common side effect of many drugs such as antibiotics, cancer chemotherapeutics or diagnostic agents and represents 20-25% of all cases of acute kidney injury (AKI). Due to a lack of representative animal models and metabolically competent r...
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University of Liverpool
2016
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.706931 |