Long range interactions regulate V(D)J recombination at the murine immunoglobulin lambda locus

V(D)J recombination generates a diverse repertoire of immunoglobulin and T cell receptor genes by mixing and matching individual V, D and J gene segments. A critical step in this process is the correct recruitment of two gene segments into a synaptic complex, but how these gene segments, which can b...

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Bibliographic Details
Main Author: Scott, James Nigel Frederyck
Other Authors: Boyes, Joan ; Tuma, Roman
Published: University of Leeds 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707044