Expression and post-translational modification of intermediate filament proteins in colonic mucosa of patients with ulcerative colitis : role in pathogenesis of colitis associated colorectal neoplasia and dysplasia
Background: Ulcerative colitis(UC) is a chronic inflammatory disease of the colon associated with increased cancer risk of colitis associated cancer(CAC). Keratins(K) are intermediate filament(IF) proteins, and are key component of the cellular cytoskeleton. K8 null mice develop colitis; a subset of...
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University of Sheffield
2016
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707074 |