Beyond SOD1 : detailed characterisation of a TDP-43 transgenic mouse model of motor neurone disease

Background: Motor neurone disease (MND) is a fatal, progressive, neurodegenerative disease causing muscle weakness, spasticity and paralysis. No small molecule drugs have translated from MND mouse models to MND patients, possibly because of MND mouse models being based on SOD1 mutations, representin...

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Bibliographic Details
Main Author: Stephenson, Jodie
Other Authors: Mead, Richard J. ; Shaw, Pamela J. ; Jenkins, Thomas
Published: University of Sheffield 2017
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707119