Nutrient-dependent effects of the autophagy-lysosomal inhibitor, Chloroquine, on cell death and lysosomal functionality
There is huge potential for targeting pro-survival autophagy as a cancer therapeutic strategy, but this approach has not yet been fully realised due to the complex involvement of autophagy for cancer biology. In early stages of transformation, autophagy acts as a tumour suppressor, whilst in a devel...
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University of Strathclyde
2017
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707296 |