Studies towards the total synthesis of (+)-retronecine and anthracimycin

This thesis consists of two separate projects. The first project involved an attempted total synthesis of (+)-retronecine A, a poisonous pyrrolizidine alkaloid via a novel asymmetric α-lithiation-substitution reaction of N-thiopivaloyl azetidine B, mediated by a chiral diamine. A total synthesis was...

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Bibliographic Details
Main Author: Smith, Joshua C.
Other Authors: O'Brien, Peter ; Clarke, Paul
Published: University of York 2016
Subjects:
547
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707483