Multisite phosphorylation in T cell receptor proximal signalling

T cell receptor proximal signalling represents a specific instance of a multisite phosphorylation system. Receptor phosphorylation is regulated by the opposing actions of the kinase LCK, and phosphatases such as CD45 and CD148. Particular phosphoforms recruit the kinase ZAP-70, which once bound, pro...

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Bibliographic Details
Main Author: Mukhopadhyay, Himadri
Other Authors: Dushek, Omer ; van der Merwe, Anton ; Maini, Philip
Published: University of Oxford 2015
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.712046