The impact of adjustment for covariates on meta-analysis of randomised intervention studies for binary outcome

Background: Covariate adjustment analysis is often used in epidemiological studies but is less common in randomised controlled trials (RCTs) and RCT meta-analyses. There is a lack of consensus on whether the analysis of RCT data should adjust for important baseline covariates. The estimated treatmen...

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Bibliographic Details
Main Author: Yu, Ly-Mee
Other Authors: Altman, Douglas
Published: University of Oxford 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.712051