Enzymatic synthesis of chemically modified DNA for analytical and diagnostic applications
Functionalised nucleotides have found widespread adoption in applications ranging from genome labelling to disease diagnostics. A popular means of introducing these modifications into nucleic acids is via the copper-catalysed azide-alkyne cycloaddition reaction. However, the toxicity of copper limit...
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University of Oxford
2015
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.712439 |