A metabolomic investigation of Rho-ROCK signalling in metastatic melanoma
Metastatic spread is the cause of 90% of cancer-related deaths. Melanoma cells with high actomyosin contractility, driven by high Rho-Rho Kinase (ROCK) signalling, exhibit a rounded amoeboid type movement and are found at the invasive fronts of primary tumours and in metastases. ROCK is a novel ther...
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King's College London (University of London)
2017
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713119 |