Identification and mechanistic study of novel drug metabolites by LC-MS

Understanding the metabolic fate of drug candidates in vitro and in vivo is a key component of drug development. Structural characterisation of drug candidate metabolites is important early in drug discovery to identify unwanted metabolic liabilities such as reactive, active, toxic or human specific...

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Bibliographic Details
Main Author: Martin, Scott
Published: Sheffield Hallam University 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713505