p62 : linking protein homeostasis and the DNA damage response during ageing

The accumulation of DNA damage has long been thought to contribute to both cellular and organismal ageing. The catabolic degradation process autophagy has also been implicated in the ageing process, as an age-dependent functional decline has been reported in many organisms. Moreover, interventions k...

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Bibliographic Details
Main Author: Hewitt, Graeme
Published: University of Newcastle upon Tyne 2016
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713830