Effects of catechol-O-methyltransferase on reinforcement learning and mesolimbic dopamine transmission
The enzyme catechol-O-methyltransferase (COMT) plays an important role in the breakdown of dopamine in prefrontal cortex (PFC), but relatively little is known about its effects on nucleus accumbens (NAc) dopamine function. In this study, a transgenic mouse model of the Val158Met polymorphism found i...
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University of Oxford
2015
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.714050 |