The contribution of ERAP1 and Natural Killer cells to the pathogenesis of Ankylosing Spondylitis
Ankylosing Spondylitis (AS) is an autoimmune condition of the sacro-iliac region at the base of the spine. The pathogenesis of the disease is unknown despite strong genetic links with HLA-B27 and ERAP1. HLA-B27 is present in ~95% of AS patients and polymorphisms within ERAP1 have been shown to disti...
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University of Southampton
2016
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.714539 |