Development and validation of assays used to evaluate STAT3 inhibitors

Transcription factors are important control proteins in cells that bind to their cognate DNA sequences in the promoter regions of genes, either up-regulating or down-regulating protein expression. In many cancer types, transcription factors are up-regulated and promote the expression of genes import...

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Bibliographic Details
Main Author: Chamberlain, Christopher Daniel
Other Authors: Thurston, David Edwin ; Rahman, Khondaker Mirazur
Published: King's College London (University of London) 2017
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.718566