Investigating the contribution of astrocytes and neuroinflammation to pathological tau changes in Alzheimer's disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterised by accumulation of ß-amyloid in extracellular plaques, intracellular neurofibrillary tangles composed of abnormally phosphorylated and aggregated tau, and widespread synaptic dysfunction and neuron loss that underlie t...

Full description

Bibliographic Details
Main Author: Phillips, Emma Claire
Other Authors: Noble, Wendy Jane ; Hanger, Diane Pamela
Published: King's College London (University of London) 2017
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.718601