Identification and characterisation of novel mechanisms that regulate TRAIL-receptor signalling complexes
Activation of death receptors by their cognate ligands can induce apoptosis through the formation of death receptor signalling complexes. TRAIL has been demonstrated to selectively induce apoptosis in transformed cells, but not normal cells, by binding to its death receptors, TRAIL-R1 and TRAIL-R2 a...
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University of Leicester
2017
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.718708 |