Signalling mechanisms contributing to integrin activation and immunological synapse formation in B cells

When a B cell encounters specific membrane-bound antigen, a series of signalling events trigger cytoskeletal rearrangements, integrin activation and cell polarisation. This, in turn, allows for B cell spreading and the formation of the immunological synapse (IS) by segregation of the B cell receptor...

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Bibliographic Details
Main Author: Vehlow, A.
Published: University College London (University of London) 2007
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.719070