The role of copper in hypoxia inducible factor-1 expression : a potential mechanism of chemical hypoxia preconditioning for ischaemia reperfusion injury

Introduction: Hypoxia Preconditioning (HPC) involves a short period of hypoxia prior to a more sustained ischaemia. This method reduces Ischaemia Reperfusion Injury (IRI) in vascular surgery. The molecular response to hypoxia and HPC is mediated by the transcription factor Hypoxia Inducible Factor 1...

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Bibliographic Details
Main Author: Richards, T.
Published: University College London (University of London) 2008
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Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.719120