Regulation of MDM2 stability and function by signalling from mTOR/S6K pathway
Ribosomal S6 kinase belongs to the AGC family of S/T kinases, which also include PKA, PKB/Akt, PKC, and SGK. The family of S6K consists of two isoforms, S6K1 and S6K2, which have cytoplasmic and nuclear splicing variants. Genetic and biochemical studies indicate that S6K is a key player in the regul...
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University College London (University of London)
2008
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.719129 |