Ligandability of protein-protein interactions and surfaces on Cullin RING E3 ubiquitin ligases

Cullin RING E3 ubiquitin ligases (CRLs) function in the ubiquitin proteasome system by catalysing the transfer of ubiquitin from E2 conjugating enzymes to specific substrate proteins. CRLs are large dynamic multi-subunit complexes that control the fate of many proteins in cells and, therefore, const...

Full description

Bibliographic Details
Main Author: Cardote, Teresa Amorim de Faria
Other Authors: Ciulli, Alessio
Published: University of Dundee 2017
Subjects:
572
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.721004