Exploring unconventional approaches to molecular replacement in protein crystallography with AMPLE

This thesis is concerned with the development and application of AMPLE, a software pipeline for macromolecular crystallographic Molecular Replacement, to different classes of proteins. The ability of AMPLE to solve protein structures via Molecular Replacement was first explored with two new classes...

Full description

Bibliographic Details
Main Author: Thomas, J. M.
Other Authors: Rigden, D. J.
Published: University of Liverpool 2016
Subjects:
572
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.721963