Characterising molecular mechanisms of Crohn's disease-associated Escherichia coli that enable their survival and replication within macrophages

Mucosa-associated adherent, invasive Escherichia coli (AIEC), found in increased number in Crohn’s disease (CD) ileal and colonic mucosae, can survive and replicate within underlying host immune competent cells (e.g. macrophages and dendritic cells) without triggering host cell death. The intra-macr...

Full description

Bibliographic Details
Main Author: Tawfik, Ahmed
Published: University of Liverpool 2016
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.721991