The role of dysregulated autophagy in Alzheimer's disease

Introduction: The accumulation of misfolded Aβ and phospho-tau are characteristic features of Alzheimer’s disease (AD) pathology. One of the cellular mechanisms responsible for the removal of these aggregates is autophagy, where proteins and organelles are degraded through the formation of autolysos...

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Bibliographic Details
Main Author: Harris, M. N.
Published: University of the West of England, Bristol 2017
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.723166