The characterization and engineering of human antigen-specific cytotoxic T cells

This D.Phil. thesis focuses on human antigen-specific cytotoxic T lymphocytes (CTLs). In the first part of the thesis, the impact of antigen stimulation strength on CTL activation was investigated by evaluating the global transcriptomes of a wellcharacterized CTL clone and some of its surface protei...

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Bibliographic Details
Main Author: Zhang, Chi
Other Authors: Dong, Tao ; McMichael, Andrew
Published: University of Oxford 2017
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.729105