Modelling of amyotrophic lateral sclerosis (ALS) using induced pluripotent stem cells (iPSC)
The hexanucleotide repeat expansion (HRE) mutation within C9orf72 gene is the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Several hypotheses have been proposed for how the mutation contributes to pathogenicity, including the loss of C9orf72 gene functi...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
University of Oxford
2017
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.729403 |