Mechanisms of Xist-dependent Polycomb recruitment
The Polycomb repressive complexes PRC1 and PRC2 play a central role in developmental gene regulation, functioning, at least in part, by catalyzing specific histone modifications, H2AK119u1 and H3K27me3, respectively. The hierarchical model of Polycomb recruitment proposes that PRC2 is recruited to t...
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University of Oxford
2017
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.729819 |