Regulation of MITF and TFEB

The bHLH-LZ transcription factors MITF and TFEB have been implicated in human disease, with their overexpression increasing the risk of developing cancer. The manner in which their access to E-box target motifs is controlled is an important consideration, as it is via binding to these motifs that bH...

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Bibliographic Details
Main Author: Friedrichsen, Hans
Other Authors: Filippakopoulos, Panagis ; Goding, Colin
Published: University of Oxford 2016
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730072