Evaluating aerosol administration of a candidate TB vaccine, MVA85A, as a way to induce potent local cellular immune responses and avoid anti-vector immunity

There is an urgent need for a better vaccine against TB than BCG, which confers variable protection against pulmonary TB. Heterologous prime-boost regimens with viral vector vaccines are a leading strategy for TB vaccine development. MVA85A is a viral vector candidate TB vaccine designed to boost BC...

Full description

Bibliographic Details
Main Author: Thomas, Zita-Rose Manjaly
Other Authors: McShane, Helen ; Satti, Iman ; Bettinson, Henry
Published: University of Oxford 2016
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730189